
UPB
Upstream Bio develops verekitug, a biologic drug candidate currently in clinical testing for inflammatory airway diseases including severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream is in early-to-mid stage development, having initiated clinical trials for verekitug and working toward FDA approval for commercial use. The company relies on third-party manufacturers to produce verekitug and plans to commercialize the drug if regulatory approval is obtained.