
KALV
KalVista Pharmaceuticals is a biopharmaceutical company focused on developing oral therapies for rare diseases, with its first approved product being EKTERLY (sebetralstat), a small molecule plasma kallikrein inhibitor for treating acute attacks of hereditary angioedema in patients aged 12 and older. EKTERLY received FDA approval in July 2025 and is the first and only oral, on-demand therapy for HAE, with efficacy demonstrated in the phase 3 KONFIDENT clinical trial published in the New England Journal of Medicine in May 2024.