
JBIO
Jade Biosciences is a clinical-stage biopharmaceutical company developing monoclonal antibody therapies to treat autoimmune diseases. Its lead candidate, JADE101, targets APRIL to treat IgA nephropathy and entered Phase 1 testing in 2025, with Phase 2 planned for mid-2026; the company also has JADE201 (targeting BAFF-R for multiple autoimmune disorders) and JADE301 in earlier development. Jade's approach focuses on improving upon existing therapies through better dosing schedules, extended half-lives using YTE technology, and enhanced potency compared to competing candidates.