
GLUE
Monte Rosa Therapeutics develops molecular glue degrader drugs designed to target proteins previously considered difficult or impossible to drug. The company is in early-stage development, with programs including MRT-2359 (targeting GSPT1), MRT-8102 (targeting NEK7), and MRT-6160 (targeting VAV1, out-licensed to Novartis), supported by its proprietary QuEEN discovery platform. Monte Rosa has partnered with Novartis to advance certain programs and is preparing to file investigational new drug applications with the FDA.