
ARWR
Arrowhead Pharmaceuticals develops medicines using RNA-targeted therapies to treat diseases. The company is advancing clinical and preclinical programs, including REDEMPLO for commercialization, along with partnership and licensing arrangements to support its research and development pipeline.
Pipeline
Plozasiran is a siRNA conjugated with GalNAc that degrades the apoC-III mRNA through the RNA interference mechanism resulting in reduced levels of hepatic and serum apoC-III protein.
Tirzepatide is a GIP receptor and GLP-1 receptor agonist. It contains a C20 fatty diacid that enables albumin binding and prolongs the half-life. Tirzepatide selectively binds to and activates both the GIP and GLP-1 receptors, the targets for native GIP and GLP-1.