
AGIO
Agios Pharmaceuticals develops and commercializes small-molecule medicines targeting pyruvate kinase (PK) enzymes, with its lead approved product PYRUKYND (mitapivat) used to treat anemia in patients with thalassemia. The company is also pursuing earlier-stage programs in other rare genetic diseases, including a PAH stabilizer candidate (AG-181) for phenylketonuria and an siRNA therapeutic (AG-236) targeting TMPRSS6. Agios has moved beyond the discovery phase and into commercialization and clinical development of multiple product candidates across different therapeutic areas.