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Conf.Conference Data

Dapiglutide Oral Phase 1b Cardiometabolic Data — ADA 2026

VKTX·dapiglutide·Obesity·
current best date
MAY–MAY
2026
WINDOW30 days
Takeaway

Phase 1b cardiometabolic biomarker data for oral dapiglutide at ADA 2026. Closest oral GLP-1 comparator in development: Lilly’s orforglipron. Watch: weight change, A1c, fasting glucose, GI tolerability at oral exposure levels.

What’s at stake

market · comparables · base rate · prior moves
Market opportunity
company filings
Peer comparables
1 readout
ClinicalTrials.gov
Stage base rate
~58%
BIO Industry Analysis 2023 (2011–2020)
Avg prior-readout move
historical price reactions
Drug
peptide
dapiglutide
INN
MoAdual GLP-1 / GIP receptor agonist

dapiglutide (VK2735) is Viking Therapeutics' dual GLP-1/GIP receptor agonist in development for weight management in adults with obesity. The drug mimics two gut hormones — GLP-1 and GIP — that regulate appetite and blood sugar, prompting the brain to reduce food intake and the body to use energy more efficiently. Viking is evaluating both a once-weekly subcutaneous injection and a daily oral formulation, targeting a competitive profile against semaglutide and tirzepatide in the Phase 3 VENTURE trial.

Indication
Obesity / GLP-1
Obesity
MeSH · D009765

No primer in glossary yet.

Source signal

This event was extracted from a primary disclosure. The full chain of citations is in the disclosure trail below.

Glossary · what this readout is measuring
2 terms detected in the takeaway
  • GLP-1target
    Glucagon-like peptide-1

    Gut hormone that triggers insulin release and slows gastric emptying. GLP-1 receptor agonists (semaglutide, tirzepatide) drive weight loss and glycemic control.

  • A1cendpoint
    Hemoglobin A1c

    Three-month average blood glucose. Standard primary endpoint in diabetes trials; absolute reduction of ≥0.5% is meaningful.

Competitive landscape

2 peers in Obesity / GLP-1 · ranked by indication + modality match
DrugCompanyModalityMechanismPhaseNext catalyst
RM-718RYTMpeptideweekly MC4R agonist (next-gen)READOUT · Oct 26
IMCIVREEsetmelanotideRYTMpeptideMC4R agonistPDUFA · Aug 26

Prior VKTX reactions to Conf. events

1 historical event · base rate, not prediction
Median 1W move
+8.2%
Median 1M move
+4.3%
Positive outcomes
1/ 1
100%
Negative outcomes
0/ 1
0%
DateHeadlineOutcome1W1M6M
Nov 2025dapiglutide — ASH Late-Breaker — Updated Survivalpositive+8.2%+4.3%+6.6%

Historical VKTX stock reaction to past Conf. catalysts. Past performance is not a forecast — base rates anchor expectations, not outcomes. Positive rate 100%.

Disclosure trail

1 observation · sorted by confidence
  1. Feb 14, 2026·2mo agopinned · highest confidence
    HIGH conf8-K
    top claim
    MAY–MAY2026
    WINDOW
    Phase 1b cardiometabolic biomarker data for the oral formulation of dapiglutide will be presented at the American Diabetes Association Scientific Sessions (May 30 – June 2, 2026).
    conf 89%via llm

MethodologyEvery catalyst date is anchored to a primary source. Disclosures with confidence ≥ 0.85 auto-publish; the rest are reviewed by a human within 24 hours. We never interpret data — we organize public information.

Disclaimer·BioSight aggregates publicly available data (SEC EDGAR, ClinicalTrials.gov, FDA, company press releases) and is provided as is for informational purposes only. Nothing here is investment, financial, legal, tax, or medical advice, or an offer to buy or sell any security. We make no warranty as to accuracy, completeness, or timeliness; dates and filings may contain errors or be superseded without notice; past events do not predict future outcomes. To the maximum extent permitted by law, BioSight, its operators, contributors, and affiliates disclaim all liability for any loss or damage arising from use of or reliance on this site. You are solely responsible for your own investment decisions — consult a licensed professional before acting on any information.

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