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Enroll.Enrollment Complete

ODYSSEY-HCM Phase 3 Enrollment Complete (nHCM)

BMY·CAMZYOS·Hypertrophic Cardiomyopathy··NCT04349072
current best date
JUN
2026
MONTH2 months
Takeaway

Procedural milestone: enrollment finishes for the Phase 3 trial of CAMZYOS in non-obstructive HCM. Anchors the Q2 2027 readout date.

What’s at stake

market · comparables · base rate · prior moves
Market opportunity
company filings
Peer comparables
1 readout
ClinicalTrials.gov
Stage base rate
~100%
BIO Industry Analysis 2023 (2011–2020)
Avg prior-readout move
historical price reactions
Drug
small molecule
CAMZYOS
mavacamten · INN
MoAcardiac myosin inhibitor

CAMZYOS (mavacamten) is a first-in-class oral cardiac myosin inhibitor developed by Bristol Myers Squibb that treats hypertrophic cardiomyopathy (HCM) — a genetic condition in which the heart muscle thickens abnormally and obstructs blood flow. The drug reduces the number of myosin-actin cross-bridges that form during each heartbeat, decreasing the force of contraction and relieving the outflow obstruction that causes breathlessness, chest pain, and syncope. CAMZYOS is approved for symptomatic obstructive HCM and is being studied in non-obstructive HCM — a distinct phenotype with twice the patient population and no approved drug therapy — in an ongoing Phase 3 trial.

Indication
Cardiology - HFpEF
Hypertrophic Cardiomyopathy
MeSH · D002311

No primer in glossary yet.

Trial
active
NCT04349072
ODYSSEY-HCM Phase 3 Mavacamten in nHCM
Phase
Ph 3
N
460
Primary completion
Oct 15, 2026

Prior BMY reactions to Enroll. events

1 historical event · base rate, not prediction
Median 1W move
+5.3%
Median 1M move
+3.9%
Positive outcomes
1/ 1
100%
Negative outcomes
0/ 1
0%
DateHeadlineOutcome1W1M6M
Jan 2026CAMZYOS — Pivotal Enrollment Completepositive+5.3%+3.9%+6.1%

Historical BMY stock reaction to past Enroll. catalysts. Past performance is not a forecast — base rates anchor expectations, not outcomes. Positive rate 100%.

Disclosure trail

1 observation · sorted by confidence
  1. Apr 22, 2026·8d agopinned · highest confidence
    HIGH confPR
    top claim
    JUN2026
    MONTH
    ODYSSEY-HCM, the Phase 3 study of CAMZYOS in non-obstructive HCM, is expected to complete enrollment in June 2026.
    conf 88%via llm

MethodologyEvery catalyst date is anchored to a primary source. Disclosures with confidence ≥ 0.85 auto-publish; the rest are reviewed by a human within 24 hours. We never interpret data — we organize public information.

Disclaimer·BioSight aggregates publicly available data (SEC EDGAR, ClinicalTrials.gov, FDA, company press releases) and is provided as is for informational purposes only. Nothing here is investment, financial, legal, tax, or medical advice, or an offer to buy or sell any security. We make no warranty as to accuracy, completeness, or timeliness; dates and filings may contain errors or be superseded without notice; past events do not predict future outcomes. To the maximum extent permitted by law, BioSight, its operators, contributors, and affiliates disclaim all liability for any loss or damage arising from use of or reliance on this site. You are solely responsible for your own investment decisions — consult a licensed professional before acting on any information.

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